The Effects of Exercise on the Tumor Immune Microenvironment

Authors

  • Ricky Siebeler Wageningen University and Research Centre
  • Vincent de Boer Wageningen University and Research Centre

DOI:

https://doi.org/10.25609/sure.v5.4178

Keywords:

Cancer, immunesystem, exercise, anti-tumor immunity

Abstract

This review explores the current understanding of the immunomodulatory effects of exercise, and the effectiveness of utilizing exercise as a therapy for cancer. Physical exercise has been shown to reduce the risk of developing cancer and appears to possess tumor-suppressive capabilities in existing solid tumors by modulating the tumor immune microenvironment. The current literature suggests exercise to enhance intra-tumoral tumor-suppressive immune cell activity through multiple pathways. The immunomodulating capabilities of exercise are likely dependent on anti-tumor immunity pathways. Exercise appears to be a viable tumor-suppressive strategy, depending on the state of anti-tumor immunity.

Additional Files

Published

2019-12-03

How to Cite

Siebeler, R., & de Boer, V. (2019). The Effects of Exercise on the Tumor Immune Microenvironment. Student Undergraduate Research E-Journal!, 5, 1–4. https://doi.org/10.25609/sure.v5.4178