Antioxidant concentrations in children with Attention Deficit Hyperactivity Disorder (ADHD)
Keywords:ADHD, neurodevelopment, biomarkers, oxidative stress, antioxidants, HPLC.
ADHD is one of the most prevalent neurodevelopmental disorder. Antioxidant concentrations are shifted in ADHD patients and antioxidant centred therapies appear to alleviate symptoms significantly1-8. This study aims to investigate antioxidant concentrations in children with ADHD of an Antwerp based population.
For the ADHD-cohort, concentrations of lipid-soluble antioxidants (a-tocopherol, g-tocopherol, retinylpalmitate, b-carotene, CoQ10 and retinol) (plasma, n = 12) and glutathione (erythrocytes, n = 4) were measured and consecutively compared to a cohort of non-ADHD children (n = 25-53). Additionally, differences in mean concentrations were compared to literature1,7,8.
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