Insulin sensitivity and fat mass in young male sedentary adults

  • Gereon Hecht Maastricht University
  • Esther Phielix Maastricht University
  • Yvo Op den Kamp Maastricht University
  • Joris Hoeks Maastricht University


We live in an obesogenic environment, spending a lot of time sitting neglecting physical activity. This study aims to determine the impact of a sedentary lifestyle on insulin sensitivity by comparing insulin sensitivity of healthy athletes and sedentary subjects. Twelve athletes and 12 sedentary subjects underwent a two-step hyperinsulinemic euglycemic clamp test to assess insulin sensitivity and a DEXA scan to assess body fat mass. Insulin sensitivity was significantly lower in sedentary subjects (p=0.009) and fat mass negatively correlated with insulin sensitivity (r=-0.57, p=0.005). This study shows that healthy sedentary subjects have an impaired insulin metabolism compared to trained athletes.

How to Cite
HECHT, Gereon et al. Insulin sensitivity and fat mass in young male sedentary adults. Student Undergraduate Research E-journal!, [S.l.], v. 4, nov. 2018. ISSN 2468-0443. Available at: <>. Date accessed: 18 feb. 2020. doi: