The Link between Salivary Surfactant-Protein D and Dementia in Nursing Home Dementia Patients

  • Celine Budding University College Roosevelt
  • Toon Holman University College Roosevelt

Abstract

Recently, serumal surfactant protein D (SP-D) has been shown to correlate with the development of dementia.
As SP-D can be measured reliably in saliva, this might provide opportunities for a non-invasive biomarker. This
preliminary study aims to determine a possible difference between the levels of salivary SP-D in nondemented
elderly and late stage demented elderly. Results indicate a significant difference between demented subjects and controls, and between male and female demented subjects. This suggests SP-D could be used as a biomarker to improve detection of dementia. Further research should focus on early-stage dementia and the role of innate immunity in dementia.

How to Cite
BUDDING, Celine; HOLMAN, Toon. The Link between Salivary Surfactant-Protein D and Dementia in Nursing Home Dementia Patients. Student Undergraduate Research E-journal!, [S.l.], v. 3, p. 205-208, dec. 2017. ISSN 2468-0443. Available at: <https://journals.open.tudelft.nl/index.php/sure/article/view/2535>. Date accessed: 22 may 2019. doi: https://doi.org/10.25609/sure.v3.2535.
Published
2017-12-05